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IMMUNOTOPE is a clinical stage biotechnology company developing immunotherapy products for the treatment and prevention of cancer and chronic viral infections. Our products activate the patient’s own immune system to fight disease and prevent recurrence. Our comprehensive approach to cancer therapy focuses on the critical, unmet need to diagnose cancer at the very earliest stages and to develop effective treatments that destroy tumors and prevent metastasis. Our product portfolio includes ovarian, breast, prostate, lung, pancreatic and colon cancer and HBV, HCV, HIV, Influenza and Dengue viral vaccines. Immunotope's platform provides the ideal combination of technologies for successful immunotherapy. We are developing products and services that will:
We use proprietary
immunoproteomics technologies to identify naturally processed
and presented antigens associated with Major Histocompatibility
Complex Class I and Class II molecules that are present only on
diseased cells. Immunotope’s
lead product is the IMT-1012
Immunotherapeutic Vaccine, a multivalent cancer
therapeutic mixture of twelve different novel antigens, each of
which targets a separate, critical pathway known to be present
in highly aggressive tumors. After successfully completing
a Phase I
clinical trial
in ovarian and breast cancer patients, Immunotope has licensed 7
antigens from IMT-1012 to Immunovaccine Inc.,
Immunotope has completed pre clinical characterization studies
and preparing for phase I clinical study in lung and pancreatic
cancer. Immunotope
is at the pre clinical stage with therapeutic vaccine
development in HCV and HIV and indications and universal
prophylactic vaccine development for influenza and dengue virus
infections.
Immunotope has partnered with Midatech Ltd, Immunotope is also applying its platform technology to develop novel autoantibody-based biomarkers for early-stage detection of cancer. Performed as a simple blood test, our products will be rapid, non-invasive and indication-specific early-stage cancer diagnostics.
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